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Padres and Astros meet with series tied 1-1

Houston Astros (82-69, first in the AL West) vs. San Diego Padres (86-66, second in the NL West) San Diego; Wednesday, 6:40 p.m. EDT PITCHING PROBABLES: Astros: Framber Valdez (14-6, 2.91 ERA, 1.

Rockies look to sweep 3-game series against the Diamondbacks

Arizona Diamondbacks (83-68, third in the NL West) vs. Colorado Rockies (59-93, fifth in the NL West) Denver; Wednesday, 3:10 p.m. EDT PITCHING PROBABLES: Diamondbacks: Eduardo Rodriguez (2-3, 5.50 ERA, 1.

Cubs and Athletics meet in series rubber match

Oakland Athletics (66-86, fourth in the AL West) vs. Chicago Cubs (77-74, second in the NL Central) Chicago; Wednesday, 2:20 p.m. EDT PITCHING PROBABLES: Athletics: Brady Basso (1-0, 1.23 ERA, 0.

Nationals take on the Mets looking to break road slide

Washington Nationals (68-83, fourth in the NL East) vs. New York Mets (83-68, second in the NL East) New York; Wednesday, 7:10 p.m. EDT PITCHING PROBABLES: Nationals: DJ Herz (4-7, 3.70 ERA, 1.21 WHIP, 98 strikeouts); Mets: Jose Quintana (9-9, 3.

Angels and White Sox meet with series tied 1-1

Chicago White Sox (36-116, fifth in the AL Central) vs. Los Angeles Angels (61-90, fifth in the AL West) Anaheim, California; Wednesday, 4:07 p.m. EDT PITCHING PROBABLES: White Sox: Jared Shuster (1-4, 4.54 ERA, 1.

Giants try to extend road win streak in matchup with the Orioles

San Francisco Giants (73-78, fourth in the NL West) vs. Baltimore Orioles (84-67, second in the AL East) Baltimore; Wednesday, 6:35 p.m. EDT PITCHING PROBABLES: Giants: Hayden Birdsong (3-5, 4.74 ERA, 1.

Brewers play the Phillies in series rubber match

Philadelphia Phillies (91-60, first in the NL East) vs. Milwaukee Brewers (87-64, first in the NL Central) Milwaukee; Wednesday, 7:40 p.m. EDT PITCHING PROBABLES: Phillies: Aaron Nola (12-8, 3.62 ERA, 1.

Tampa Bay Rays and Boston Red Sox meet in game 2 of series

Boston Red Sox (75-76, third in the AL East) vs. Tampa Bay Rays (74-77, fourth in the AL East) St. Petersburg, Florida; Wednesday, 6:50 p.m. EDT PITCHING PROBABLES: Red Sox: Tanner Houck (8-10, 3.24 ERA, 1.

Tigers bring 4-game road win streak into game against the Royals

Detroit Tigers (79-73, fourth in the AL Central) vs. Kansas City Royals (82-70, second in the AL Central) Kansas City, Missouri; Wednesday, 7:40 p.m. EDT PITCHING PROBABLES: Tigers: Tarik Skubal (16-4, 2.50 ERA, 0.

Rangers host the Blue Jays on home winning streak

Toronto Blue Jays (72-79, fifth in the AL East) vs. Texas Rangers (72-79, third in the AL West) Arlington, Texas; Wednesday, 8:05 p.m. EDT PITCHING PROBABLES: Blue Jays: Bowden Francis (8-4, 3.50 ERA, 0.
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